Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 12/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12532786 | 0.86 | BCL2 (0.59) | BCL2PTPN1ITGB3ITGA2BREN | |
| SCHEMBL19930027 | 0.86 | BCL2 (0.59) | BCL2PTPN1ITGB3ITGA2BREN | |
| SCHEMBL8732948 | 0.83 | PTPN1 (0.48) | BCL2PTPN1ACACBITGB3ITGA2B | |
| SCHEMBL8758574 | 0.83 | ACACB (0.51) | ACACB | |
| SCHEMBL8732292 | 0.81 | ACACB (0.48) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8732428 | 0.79 | HDAC8 (0.53) | BCL2PTPN1ACACBITGB3ITGA2B | |
| SCHEMBL15764483 | 0.79 | ACACB (0.62) | ACACBITGB3ITGA2B | |
| SCHEMBL8732422 | 0.79 | HDAC8 (0.53) | BCL2PTPN1ACACBITGB3ITGA2B | |
| SCHEMBL9627603 | 0.78 | MAOB (0.56) | — | |
| SCHEMBL12203612 | 0.78 | ACACB (0.58) | ACACBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |