Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650533 | 0.91 | ITGB3 (0.57) | ACACBITGB3ITGA2B | |
| SCHEMBL9650513 | 0.90 | ITGB3 (0.56) | ACACBITGB3ITGA2B | |
| SCHEMBL9650211 | 0.90 | ITGB3 (0.56) | ACACBITGB3ITGA2B | |
| SCHEMBL256796 | 0.86 | ACACB (0.62) | ACACB | |
| SCHEMBL8246768 | 0.85 | ITGB3 (0.56) | ACACBITGB3ITGA2B | |
| SCHEMBL6685168 | 0.85 | ITGB3 (0.79) | ITGB3ITGA2B | |
| SCHEMBL14051416 | 0.85 | ITGB3 (0.56) | ACACBITGB3ITGA2B | |
| SCHEMBL6998950 | 0.85 | ITGB3 (0.79) | ITGB3ITGA2B | |
| SCHEMBL8732422 | 0.85 | HDAC8 (0.53) | ACACBITGB3ITGA2B | |
| SCHEMBL8732428 | 0.85 | HDAC8 (0.53) | ACACBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155355-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY, INC. | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155355-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | ACACB 85/4885ITGB3 4047/4885ITGA2B 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.