Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732073 | 0.91 | LTB4R (0.74) | LTB4R | |
| SCHEMBL9334167 | 0.86 | LTB4R (0.66) | LTB4R | |
| SCHEMBL8073433 | 0.85 | LTB4R (0.64) | LTB4R | |
| SCHEMBL9334194 | 0.83 | LTB4R (0.63) | LTB4R | |
| SCHEMBL9333861 | 0.82 | LTB4R (0.69) | LTB4R | |
| Lithium Ion SCHEMBL9336839 | 0.81 | LTB4R (0.61) | LTB4R | |
| SCHEMBL9333838 | 0.81 | LTB4R (0.64) | LTB4R | |
| SCHEMBL9335116 | 0.81 | LTB4R (0.66) | LTB4R | |
| SCHEMBL9334198 | 0.81 | LTB4R (0.62) | LTB4R | |
| SCHEMBL9373822 | 0.81 | LTB4R (0.60) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812194-A4 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORP (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0812194-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026725-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-06 | — | — | WO | disclosed |