Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795839 | 0.89 | KMT2A (0.53) | KMT2ADAOALDH1A1LMNARAB9A | |
| SCHEMBL8729255 | 0.80 | KMT2A (0.38) | KMT2ANAMPTSORT1VNN1GSK3B | |
| SCHEMBL1574186 | 0.75 | CYP19A1 (0.50) | ALDH1A1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL19555418 | 0.75 | KMT2A (0.54) | KMT2ADAOALDH1A1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL6012017 | 0.73 | KMT2A (0.53) | KMT2ADAOALDH1A1LMNARAB9A | |
| SCHEMBL2309516 | 0.73 | KMT2A (0.62) | KMT2ADAOALDH1A1LMNARAB9A | |
| SCHEMBL26046022 | 0.73 | KMT2A (0.53) | KMT2ADAOALDH1A1LMNARAB9A | |
| SCHEMBL23775038 | 0.71 | RAB9A (0.46) | NAMPTSORT1VNN1GSK3BKDR | |
| SCHEMBL6282286 | 0.70 | PTPN1 (0.56) | NAMPTSORT1GSK3BHIF1AEPAS1 | |
| SCHEMBL6795841 | 0.68 | KMT2A (0.46) | KMT2ADAOALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |