Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528342 | 0.76 | CES2 (0.64) | CES2NSD2BCHEACHECES1 | |
| SCHEMBL14902046 | 0.73 | CES2 (0.56) | CES2NSD2BCHEACHECES1 | |
| SCHEMBL9242978 | 0.71 | — | — | |
| SCHEMBL11415970 | 0.61 | CES2 (0.57) | CES2NSD2BCHEACHECES1 | |
| SCHEMBL11730161 | 0.57 | — | — | |
| SCHEMBL11880682 | 0.56 | CES2 (0.39) | CES2NSD2BCHEACHECES1 | |
| Calcium Chloride SCHEMBL28622754 | 0.52 | — | — | |
| SCHEMBL21327556 | 0.50 | CES2 (0.90) | CES2NSD2BCHEACHECES1 | |
| Calcium Chloride SCHEMBL5381230 | 0.47 | — | — | |
| SCHEMBL11780398 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553467-B1 | Low-hysteresis elastomer compositions using amino-substituted aryllithium polymerization initiators | BRIDGESTONE CORP (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0736551-A1 | Low-hysteresis elastomer compositions using amino-substituted aryllithium polymerization intiators | BRIDGESTONE CORPORATION (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736550-A1 | Low-hysteresis elastomer compositions using amino-substituted aryllithium polymerization initiators | BRIDGESTONE CORPORATION (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5523371-A | DIENE HOMO OR COPOLYMER WITH MONOVINYL AROMATIC POLYMER AND CARRYING AMINO FUNCTIONAL GROUP ONE END OF CHAIN AND LITHIUM AROMATIC COMPOUND AT OTHER END; USED FOR PNEUMATIC TIRES | BRIDGESTONE CORPORATION (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5519086-A | PNEUMATIC TIRES | BRIDGESTONE CORPORATION (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5436290-A | Low-hysteresis elastomer compositions using amino-substituted aryllithium polymerization initiators | BRIDGESTONE CORPORATION (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5420219-A | Diene homo and copolymers with vinylaromatic compounds | BRIDGESTONE CORPORTION (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5274106-A | Amino-substituted aryllithium compounds as anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0553467-A1 | Low-hysteresis elastomer compositions using amino-substituted aryllithium polymerization initiators | BRIDGESTONE CORPORATION (JP) | 1993-08-04 | — | — | EP | disclosed |