Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.40 |
| ▸ | CTRC | Q99895 | 5/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359565 | 0.93 | F2 (0.39) | F2CTRCPRSS2KAT6A | |
| SCHEMBL7537667 | 0.93 | F2 (0.39) | F2CTRCPRSS2 | |
| SCHEMBL7360906 | 0.91 | F2 (0.47) | F2CTRCPRSS2 | |
| SCHEMBL7356096 | 0.89 | F2 (0.39) | F2CTRCPRSS2KAT6A | |
| SCHEMBL7363720 | 0.86 | F2 (0.34) | F2CTRCPRSS2KAT6ANPC1 | |
| SCHEMBL8726659 | 0.83 | F2 (0.58) | F2CTRCPRSS2 | |
| SCHEMBL7359257 | 0.80 | F2 (0.35) | F2 | |
| SCHEMBL7479980 | 0.80 | F2 (0.34) | F2 | |
| SCHEMBL7391086 | 0.79 | F2 (0.40) | F2CTRCPRSS2NPC1 | |
| SCHEMBL8726831 | 0.79 | F2 (0.40) | F2CTRCPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778839-B1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |