Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359257 | 0.93 | F2 (0.35) | F2 | |
| SCHEMBL7479980 | 0.92 | F2 (0.34) | F2 | |
| SCHEMBL8728793 | 0.91 | F2 (0.41) | F2ARALDH1A1MAPTTRPV4 | |
| SCHEMBL7357199 | 0.89 | BRPF1 (0.34) | F2KAT6A | |
| SCHEMBL8729631 | 0.86 | F2 (0.40) | F2KAT6ANPC1PRSS2CTRC | |
| SCHEMBL7359565 | 0.79 | F2 (0.39) | F2KAT6APRSS2CTRC | |
| SCHEMBL8726659 | 0.79 | F2 (0.58) | F2POLBPRSS2CTRC | |
| SCHEMBL7537667 | 0.79 | F2 (0.39) | F2PRSS2CTRC | |
| SCHEMBL7538371 | 0.78 | BRD4 (0.38) | ALDH1A1BRD4MAPTTSHRL3MBTL1 | |
| SCHEMBL7360906 | 0.77 | F2 (0.47) | F2PRSS2CTRCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |
| EP-0778839-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006849-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |