Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699146 | 0.85 | TSHR (0.47) | TSHRKDM4EHSD17B10NPC1TP53 | |
| SCHEMBL1713613 | 0.72 | CRBN (0.44) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL32688313 | 0.72 | CRBN (0.44) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL839645 | 0.67 | KDM4E (0.61) | TSHRKDM4EHSD17B10NPC1TP53 | |
| SCHEMBL14974497 | 0.67 | KDM4E (0.41) | TSHRKDM4EHSD17B10NPC1TP53 | |
| SCHEMBL31249024 | 0.67 | KDM4E (0.61) | TSHRKDM4EHSD17B10NPC1TP53 | |
| SCHEMBL1713450 | 0.66 | TSHR (0.42) | TSHRKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5142126 | 0.66 | ALDH1A1 (0.47) | TSHRKDM4EHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL8797169 | 0.65 | ALPI (0.41) | TSHRKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL840080 | 0.64 | KDM4E (0.63) | TSHRKDM4EHSD17B10NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |