Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786223 | 0.85 | MAPT (0.57) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL10804813 | 0.84 | ALDH1A1 (0.51) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4455295 | 0.84 | CA1 (0.65) | KDM4EHTTLMNAALDH1A1CA1 | |
| SCHEMBL21374189 | 0.81 | ALDH1A1 (0.57) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL9667921 | 0.81 | KDM4E (0.77) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL30037411 | 0.80 | MAPT (0.51) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3549964 | 0.80 | MAPT (0.51) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.80 | MAPT (0.86) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.80 | MAPT (0.86) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL17593678 | 0.79 | KDM4E (0.57) | MAPTKMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |