SCHEMBL8730099

SCHEMBL8730099

COc1ccc(S(=O)(=O)NCC2Cc3ccc(CC(=O)O)cc3C2)cc1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 14/20 0.66
TSHR P16473 1/20 0.52
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8757138 0.89 TBXA2R (0.62) TBXA2RTSHRMEN1KMT2A
SCHEMBL8730165 0.88 TBXA2R (0.70) TBXA2R
SCHEMBL8734691 0.88 TBXA2R (0.70) TBXA2RMEN1KMT2A
SCHEMBL8730117 0.88 TBXA2R (0.61) TBXA2RTSHR
SCHEMBL8758402 0.88 TBXA2R (0.63) TBXA2RTSHRMEN1KMT2A
SCHEMBL8733764 0.87 TBXA2R (0.61) TBXA2R
SCHEMBL8734705 0.87 TBXA2R (0.64) TBXA2R
SCHEMBL8731670 0.86 TBXA2R (0.82) TBXA2RMEN1KMT2A
SCHEMBL8733707 0.86 TBXA2R (0.53) TBXA2RTSHRMEN1KMT2A
SCHEMBL10405581 0.86 TBXA2R (0.61) TBXA2RTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750524-A ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0773019-A1 HYPERLIPEMIA REMEDY ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-05-14 EP disclosed