SCHEMBL8730165

SCHEMBL8730165

CCc1ccc(S(=O)(=O)NCC2Cc3ccc(CC(=O)O)cc3C2)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 16/20 0.70
MEP1B Q16820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734691 0.91 TBXA2R (0.70) TBXA2R
SCHEMBL8731670 0.89 TBXA2R (0.82) TBXA2R
SCHEMBL8733779 0.88 TBXA2R (0.70) TBXA2RMEP1B
SCHEMBL8730048 0.88 TBXA2R (0.70) TBXA2R
SCHEMBL5673556 0.88 TBXA2R (0.85) TBXA2R
SCHEMBL8734661 0.88 TBXA2R (0.70) TBXA2RMEP1B
SCHEMBL8728418 0.88 TBXA2R (0.66) TBXA2R
SCHEMBL8730099 0.88 TBXA2R (0.66) TBXA2R
SCHEMBL8733556 0.87 TBXA2R (0.62) TBXA2R
SCHEMBL8730117 0.86 TBXA2R (0.61) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750524-A ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0773019-A1 HYPERLIPEMIA REMEDY ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-05-14 EP disclosed