Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735578 | 0.92 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8733910 | 0.86 | KDM4E (0.55) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8059291 | 0.84 | KDM4E (0.62) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8057366 | 0.83 | KDM4E (0.53) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8057434 | 0.80 | KDM4E (0.50) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8058583 | 0.78 | KDM4E (0.48) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8064229 | 0.76 | KDM4E (0.48) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8064088 | 0.76 | KDM4E (0.58) | KDM4EDRD3PIK3CGALDH1A1HPGD | |
| SCHEMBL8733605 | 0.75 | STAT3 (0.45) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8059277 | 0.75 | KDM4E (0.49) | KDM4EDRD3PIK3CGALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |