Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059291 | 0.95 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8057366 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8057434 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8730261 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8736312 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8064088 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8058583 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8064229 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8058512 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10PIK3CG | |
| SCHEMBL8059277 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |