SCHEMBL8730337

SCHEMBL8730337

C=Cc1ccc(C2CCC(c3ccc(COCC)cc3)CC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 9/20 0.36
ESR2 Q92731 3/20 0.35
SLC6A4 P31645 1/20 0.34
ALDH1A1 P00352 1/20 0.33
APLNR P35414 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
SPHK2 Q9NRA0 5/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8730330 1.00 SPHK1 (0.36) SPHK1ESR2SLC6A4ALDH1A1APLNR
SCHEMBL8727324 0.88 SPHK1 (0.38) SPHK1ESR2SLC6A4SPHK2
SCHEMBL8727320 0.88 SPHK1 (0.38) SPHK1ESR2SLC6A4SPHK2
SCHEMBL8730879 0.87 SPHK1 (0.43) SPHK1SPHK2
SCHEMBL8730887 0.87 SPHK1 (0.43) SPHK1SPHK2
SCHEMBL8728612 0.86 SPHK1 (0.45) SPHK1SPHK2
SCHEMBL8728616 0.86 SPHK1 (0.45) SPHK1SPHK2
SCHEMBL91630 0.85 ALDH1A1 (0.46) ALDH1A1
SCHEMBL8732393 0.85 ALDH1A1 (0.41) SPHK1ESR2ALDH1A1APLNRESR1
SCHEMBL8725734 0.85 SPHK1 (0.36) SPHK1ESR2APLNRESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed