SCHEMBL8730449

SCHEMBL8730449

CC(=O)OC1CCC(C2CCC(c3ccccc3)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 5/20 0.51
AKR1C3 P42330 1/20 0.44
AKR1C1 Q04828 1/20 0.44
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HCRTR2 O43614 4/20 0.40
NPY5R Q15761 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8730453 1.00 SLC18A3 (0.51) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL8384792 0.95 SLC18A3 (0.55) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL28372457 0.89 SLC18A3 (0.53) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL8725348 0.84 SLC18A3 (0.37) SLC18A3
SCHEMBL8725355 0.84 SLC18A3 (0.37) SLC18A3
SCHEMBL8725353 0.84 SLC18A3 (0.37) SLC18A3
SCHEMBL21826434 0.81 AKR1C3 (0.50) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL21826495 0.81 AKR1C3 (0.50) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL21826494 0.81 AKR1C3 (0.50) SLC18A3AKR1C3AKR1C1NPC1RAB9A
SCHEMBL21826435 0.81 AKR1C3 (0.50) SLC18A3AKR1C3AKR1C1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed