SCHEMBL8725348

SCHEMBL8725348

CC(=O)OC1CCC([C@H]2CC[C@H](c3ccc(I)cc3)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 3/20 0.37
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
SLC6A4 P31645 6/20 0.35
SLC6A3 Q01959 6/20 0.35
SLC6A2 P23975 4/20 0.35
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8725355 1.00 SLC18A3 (0.37) SLC18A3PTPN2PTPN1SLC6A4SLC6A3
SCHEMBL8725353 1.00 SLC18A3 (0.37) SLC18A3PTPN2PTPN1SLC6A4SLC6A3
SCHEMBL9474242 0.95 SLC18A3 (0.40) SLC18A3PTPN2PTPN1SLC6A4SLC6A3
SCHEMBL9474246 0.95 SLC18A3 (0.40) SLC18A3PTPN2PTPN1SLC6A4SLC6A3
SCHEMBL8730449 0.84 SLC18A3 (0.51) SLC18A3
SCHEMBL8730453 0.84 SLC18A3 (0.51) SLC18A3
SCHEMBL8725472 0.81 HSD11B1 (0.41)
SCHEMBL8725467 0.81 HSD11B1 (0.41)
SCHEMBL8725475 0.81 HSD11B1 (0.41)
SCHEMBL5246202 0.81 ESR2 (0.55) ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed