Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.50 |
| ▸ | RARG | P13631 | 12/20 | 0.50 |
| ▸ | RARA | P10276 | 10/20 | 0.50 |
| ▸ | RXRA | P19793 | 10/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585571 | 0.85 | RARB (0.53) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9118270 | 0.79 | RARB (0.48) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL15703739 | 0.79 | RARB (0.54) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8731006 | 0.78 | RARB (0.58) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3838099 | 0.77 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8902795 | 0.76 | RARB (0.59) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8902801 | 0.76 | RARB (0.59) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9118275 | 0.74 | RARB (0.54) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7548252 | 0.73 | RARB (0.69) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7548239 | 0.73 | RARB (0.69) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | Centre Europeen de Bioprospective -CEB (FR) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997026237-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CENTRE EUROPEEN DE BIOPROSPECTIVE - CEB (FR) | 1997-07-24 | — | — | WO | disclosed |