Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.53 |
| ▸ | RARG | P13631 | 11/20 | 0.53 |
| ▸ | RARA | P10276 | 9/20 | 0.53 |
| ▸ | RXRA | P19793 | 10/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730892 | 0.85 | RARB (0.50) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9118270 | 0.82 | RARB (0.48) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL15703739 | 0.82 | RARB (0.54) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7544450 | 0.81 | RARG (0.73) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7544452 | 0.81 | RARG (0.73) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8731006 | 0.81 | RARB (0.58) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3838099 | 0.80 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8902795 | 0.78 | RARB (0.59) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8902801 | 0.78 | RARB (0.59) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7544453 | 0.78 | RARG (0.73) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957605-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-1957603-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| CN-101326260-B | Organic electroluminescent device | MERCK PATENT GMBH | 2012-08-15 | — | — | CN | disclosed |
| CN-101326260-A | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2008-12-17 | — | — | CN | disclosed |
| CN-101326261-A | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2008-12-17 | — | — | CN | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1957605-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1957603-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007065549-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007065547-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | RARB 1540/4885RARG 2167/4885RARA 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.