SCHEMBL8730901

SCHEMBL8730901

C=Cc1ccc(C2CCC(c3ccc(COCC=CC)cc3)CC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
ALOX5 P09917 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8730897 1.00 ESR2 (0.31) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8730895 1.00 ESR2 (0.31) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8730709 0.88 SPHK1 (0.33) ESR2SPHK1
SCHEMBL8730701 0.88 SPHK1 (0.33) ESR2SPHK1
SCHEMBL8730694 0.88 SPHK1 (0.33) ESR2SPHK1
SCHEMBL8732182 0.88 HTR2A (0.36) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8732178 0.88 HTR2A (0.36) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8732183 0.88 HTR2A (0.36) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8732177 0.88 HTR2A (0.36) ESR2SPHK1HTR2AHTR2CHTR2B
SCHEMBL8725420 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed