Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730964 | 0.86 | FAAH (0.44) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL8735081 | 0.85 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL2626945 | 0.85 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL25317885 | 0.85 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL30518974 | 0.85 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL25410597 | 0.85 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL734321 | 0.83 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL8058782 | 0.83 | FAAH (0.43) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL9615224 | 0.81 | FAAH (0.40) | FAAHALDH1A1EPHX2MAPTHPGD | |
| SCHEMBL8733944 | 0.81 | KMT2A (0.42) | FAAHALDH1A1EPHX2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497972-B1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX INC (US) | 1998-12-23 | — | — | EP | disclosed |
| EP-0497972-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1992004341-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-03-19 | — | — | WO | disclosed |