SCHEMBL8730928

SCHEMBL8730928

CCCCCCCC(=O)OCCC(C)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.69
MAPT P10636 1/20 0.69
DNM1 Q05193 1/20 0.57
LMNA P02545 4/20 0.56
KDM4E B2RXH2 1/20 0.56
DUSP3 P51452 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
PAM P19021 2/20 0.53
ALDH1A1 P00352 1/20 0.53
TSHR P16473 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
LPAR6 P43657 1/20 0.49
LPAR1 Q92633 1/20 0.49
LPAR4 Q99677 1/20 0.49
LPAR5 Q9H1C0 1/20 0.49
LPAR2 Q9HBW0 1/20 0.49
LPAR3 Q9UBY5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35584 1.00 DGKA (0.69) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL2864987 1.00 DGKA (0.69) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL10512716 0.98 MAPT (0.66) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL10781722 0.93 MAPT (0.59) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL9730363 0.91 DGKA (0.67) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL1197391 0.91 DGKA (0.62) DGKAMAPTMEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL7163141 0.91 MAPT (0.58) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL12076454 0.91 MAPT (0.53) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL29074117 0.90 MAPT (0.65) DGKAMAPTDNM1LMNAKDM4E
SCHEMBL18641642 0.90 MAPT (0.65) DGKAMAPTDNM1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4423072-A ADMINISTERING A DIHYDROXYALKANOL, A MONO-OR DIESTER, OR LA TRIGLYCERIDE TO PREGNANT SOW THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1983-12-27 US claimed
US-4329359-A USING A GLYCOL, A TRIBLYCERIDE OR AN ESTER UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1982-05-11 US claimed
WO-1998019545-A1 COMPOSITION AND METHOD FOR THE TREATMENT OF VAGINAL YEAST INFECTIONS REINHARD MARK S (US) 1998-05-14 WO disclosed
US-5573765-A LACTOBACILLUS, ACETATE BUFFER Reinhard, Mark S. (US) 1996-11-12 US disclosed
US-5340836-A A cleaning solution consisting of ethylene glycol, propylene glycol, glycerol and buffered aqueous acetate; fungicides for treating urogenital disorders Reinhard, Mark S. (US) 1994-08-23 US disclosed
US-4423072-A ADMINISTERING A DIHYDROXYALKANOL, A MONO-OR DIESTER, OR LA TRIGLYCERIDE TO PREGNANT SOW THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1983-12-27 US disclosed
US-4329359-A USING A GLYCOL, A TRIBLYCERIDE OR AN ESTER UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1982-05-11 US disclosed