Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.85 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.85 |
| ▸ | PGR | P06401 | 2/20 | 0.85 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | SHBG | P04278 | 1/20 | 0.85 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | AR | P10275 | 1/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731184 | 1.00 | HIF1A (0.85) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL10292969 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL6370134 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL13202859 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL13046615 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL24900238 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL15114813 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL12396665 | 0.92 | HIF1A (0.85) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL22476662 | 0.92 | HIF1A (0.85) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrocortisone SCHEMBL10261067 | 0.92 | HIF1A (1.00) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648229-B1 | HYALURONIC ACID AND DERIVATIVES THEREOF IN INTERPENETRATING POLYMER NETWORKS (IPN) | MURST ITALIAN (IT) | 1998-05-06 | — | — | EP | disclosed |
| US-5644049-A | Biomaterial comprising hyaluronic acid and derivatives thereof in interpenetrating polymer networks (IPN) | M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITITES AND SCIENTIFIC AND TECHNOLOGY RESEARCH (IT) | 1997-07-01 | — | — | US | disclosed |