SCHEMBL8731307

SCHEMBL8731307

CCCCC[SiH]1CCC(CCc2ccc(-c3cc(F)c(/C(F)=C/F)c(F)c3)cc2)CC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.37
RARA P10276 1/20 0.37
RARG P13631 1/20 0.37
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731315 1.00 RARB (0.37) RARBRARARARGGPR84
SCHEMBL8731311 1.00 RARB (0.37) RARBRARARARGGPR84
SCHEMBL8727677 0.90
SCHEMBL8727683 0.90
SCHEMBL8727670 0.90
SCHEMBL7766387 0.84 RARB (0.42) RARBRARARARGGPR84
SCHEMBL8021447 0.84 RARB (0.42) RARBRARARARGGPR84
SCHEMBL8021444 0.84 RARB (0.42) RARBRARARARGGPR84
SCHEMBL7766389 0.84 RARB (0.42) RARBRARARARGGPR84
SCHEMBL8728604 0.83 THRA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
EP-0742222-A2 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-11-13 EP disclosed