Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1270344 | 0.92 | RECQL (0.38) | RECQLHPGDMAPK1TSHRGLA | |
| SCHEMBL5685448 | 0.90 | RECQL (0.37) | RECQLHPGDMAPK1TSHRGLA | |
| Sulfamate SCHEMBL29029038 | 0.87 | CA2 (0.39) | RECQLHPGDMAPK1TSHRGLA | |
| Sulfuric Acid SCHEMBL7701903 | 0.84 | RECQL (0.41) | RECQLHPGDMAPK1TSHRGLA | |
| Sulfuric Acid SCHEMBL10480014 | 0.82 | RECQL (0.45) | RECQLHPGDMAPK1TSHRGLA | |
| SCHEMBL16061134 | 0.81 | RECQL (0.32) | RECQLHPGDMAPK1TSHRGLA | |
| Trifluoromethanesulfonic Acid SCHEMBL9365930 | 0.81 | KCNH2 (0.42) | RECQLHPGDMAPK1TSHRGLA | |
| SCHEMBL467289 | 0.80 | TSHR (0.40) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL5132102 | 0.80 | TSHR (0.40) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL11604700 | 0.80 | RECQL (0.32) | RECQLHPGDMAPK1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837761-A1 | AQUEOUS ANTI-MICROBIAL COMPOSITIONS CONTAINING ORGANOTIN COMPOUNDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001423-A1 | AQUEOUS ANTI-MICROBIAL COMPOSITIONS CONTAINING ORGANOTIN COMPOUNDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |