Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574596 | 0.85 | POLB (0.39) | POLBMCOLN3ALDH1A1HPGDABL1 | |
| SCHEMBL8724651 | 0.83 | KDM4E (0.36) | POLBMCOLN3ALDH1A1HPGDABL1 | |
| SCHEMBL7584530 | 0.82 | POLB (0.40) | POLBMCOLN3ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7572960 | 0.79 | ABL1 (0.41) | POLBMCOLN3ALDH1A1HPGDABL1 | |
| SCHEMBL27326189 | 0.76 | POLB (0.39) | POLBMCOLN3ALDH1A1HPGDABL1 | |
| SCHEMBL29665109 | 0.73 | ABL1 (0.46) | ALDH1A1HPGDL3MBTL1ABL1TSHR | |
| SCHEMBL8389312 | 0.71 | ABL1 (0.40) | POLBMCOLN3ALDH1A1HPGDABL1 | |
| SCHEMBL27326191 | 0.71 | ABL1 (0.40) | ALDH1A1HPGDL3MBTL1ABL1MRGPRX4 | |
| SCHEMBL8488636 | 0.71 | ABL1 (0.45) | ALDH1A1HPGDL3MBTL1ABL1MRGPRX4 | |
| SCHEMBL8492639 | 0.71 | ABL1 (0.45) | ALDH1A1HPGDL3MBTL1ABL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |