Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584530 | 0.86 | POLB (0.40) | POLBMCOLN3ABL1MRGPRX4ALDH1A1 | |
| SCHEMBL8731572 | 0.85 | POLB (0.37) | POLBMCOLN3ABL1MRGPRX4ALDH1A1 | |
| SCHEMBL7572981 | 0.82 | ABL1 (0.39) | POLBMCOLN3ABL1ALDH1A1RXFP1 | |
| SCHEMBL7574592 | 0.82 | ABL1 (0.39) | POLBABL1ALDH1A1TSHRMEN1 | |
| SCHEMBL7572960 | 0.82 | ABL1 (0.41) | POLBMCOLN3ABL1MRGPRX4ALDH1A1 | |
| SCHEMBL7578223 | 0.82 | ABL1 (0.41) | ABL1ALDH1A1RXFP1TSHRMEN1 | |
| SCHEMBL27326189 | 0.79 | POLB (0.39) | POLBMCOLN3ABL1MRGPRX4ALDH1A1 | |
| SCHEMBL8729830 | 0.79 | CES2 (0.42) | POLBMCOLN3ABL1ALDH1A1TSHR | |
| SCHEMBL8391653 | 0.77 | ABL1 (0.41) | ABL1MRGPRX4ALDH1A1RXFP1TSHR | |
| SCHEMBL8389312 | 0.75 | ABL1 (0.40) | POLBMCOLN3ABL1MRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |