Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105809 | 0.82 | NPC1 (0.41) | NISCHNPC1ADRA2ASMN1; SMN2 | |
| SCHEMBL13517962 | 0.80 | KCNH2 (0.50) | NISCHRAB9ANPC1HPGDKDM4E | |
| SCHEMBL20410845 | 0.79 | NPC1 (0.39) | NISCHNPC1SMN1; SMN2 | |
| SCHEMBL7459026 | 0.79 | KCNH2 (0.45) | — | |
| SCHEMBL1338566 | 0.78 | NISCH (0.47) | NISCHRAB9ANPC1HPGDKMT2A | |
| SCHEMBL27260114 | 0.76 | NISCH (0.46) | NISCHNPC1ADRA2AMAOASMN1; SMN2 | |
| Carbimide SCHEMBL29055881 | 0.76 | NPC1 (0.37) | NISCHNPC1SMN1; SMN2 | |
| SCHEMBL10520530 | 0.76 | KCNH2 (0.38) | NPC1SMN1; SMN2 | |
| SCHEMBL23054974 | 0.75 | KCNH2 (0.37) | NPC1 | |
| SCHEMBL29364765 | 0.75 | CHRNB4 (0.47) | RAB9ANPC1HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003231-A | Novel method for preparing phenylcyclopropylamine derivatives and use thereof for preparing ticagrelor | ACTAVIS GROUP PTC EHF | 2013-03-27 | — | — | CN | disclosed |
| CN-101255209-A | Diene polymer and process for producing the same | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-100408553-C | Method for producing optically active cycloalkylidenebisoxazoline compound and intermediate of the same | SUMITOMO CHEMICAL CO (JP) | 2008-08-06 | — | — | CN | disclosed |
| CN-1898196-A | Process for producing optically active cycloalkylidenebisoxazoline compound and intermediate of the compound | SUMITOMO CHEMICAL CO (JP) | 2007-01-17 | — | — | CN | disclosed |
| CN-1259322-C | Asymmetric copper compound and cyclopropanation reaction with it | SUMITOMO CHEMICAL CO (JP) | 2006-06-14 | — | — | CN | disclosed |
| CN-1771236-A | Optically active bisoxazoline compound, process for producing the same, and use thereof | SUMITOMO CHEMICAL CO (JP) | 2006-05-10 | — | — | CN | disclosed |
| CN-1231456-C | Process for preparing optically active cyclopropyl carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1480448-A | Process for preparing optically active cyclopropyl carboxylic acid derivative | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1134422-C | Optically active bisoxazoline compounds, process for their preparation and their use | ������������ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| CN-1384105-A | Asymmetric copper compound and cyclopropanation reaction with it | SUMITOMO CHEMICAL CO (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1210858-A | Optically active bisoxazoline compounds, process for their preparation and their use | SUMITOMO CHEMICAL CO (JP) | 1999-03-17 | — | — | CN | disclosed |
| US-5830948-A | Polymerizable macromonomers and polymers prepared therefrom | CORNELL RESEARCH FOUNDATION, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| US-5635571-A | Polymerizable macromonomers and polymers prepared therefrom | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0470104-A1 | A PROCESS FOR MAKING 2-OXAZOLINES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-02-12 | — | — | EP | disclosed |
| WO-1990013546-A1 | A PROCESS FOR MAKING 2-OXAZOLINES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-11-15 | — | — | WO | disclosed |
| EP-0394849-A1 | Process for the preparation of 2-oxazolines | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-10-31 | — | — | EP | disclosed |