Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.34 |
| ▸ | PPP5C | P53041 | 1/20 | 0.34 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603324 | 0.87 | TP53 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL121208 | 0.76 | — | — | |
| SCHEMBL16691533 | 0.76 | — | — | |
| SCHEMBL1515015 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL14275646 | 0.76 | TP53 (0.33) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL11100210 | 0.75 | FKBP4 (0.32) | KMT2A | |
| SCHEMBL19526372 | 0.73 | — | — | |
| SCHEMBL5521154 | 0.70 | TP53 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL1219605 | 0.70 | CA1 (0.40) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL23645791 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212773-A | Perfumery compositions with trimethyl-tetrahydropyran-2-ones | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-07-15 | — | — | US | claimed |
| EP-0004978-A1 | Use of 4,6,6-trimethyltetrahydropyran-2-one and a mixture thereof with 4,4,6-trimethyltetrahydropyran-2-one in a weight ratio of 60:40 as fragrances and fragrant compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1979-10-31 | — | — | EP | claimed |
| EP-2618856-A1 | DEODORANT COMPOSITION FOR SULFIDES | Takasago International Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012039516-A1 | DEODORANT COMPOSITION FOR SULFIDES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-03-29 | — | — | WO | disclosed |
| US-4212773-A | Perfumery compositions with trimethyl-tetrahydropyran-2-ones | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-07-15 | — | — | US | disclosed |
| US-4212773-A | Perfumery compositions with trimethyl-tetrahydropyran-2-ones | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-07-15 | — | — | US | disclosed |
| US-4212773-A | Perfumery compositions with trimethyl-tetrahydropyran-2-ones | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0004978-A1 | Use of 4,6,6-trimethyltetrahydropyran-2-one and a mixture thereof with 4,4,6-trimethyltetrahydropyran-2-one in a weight ratio of 60:40 as fragrances and fragrant compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1979-10-31 | — | — | EP | disclosed |