Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733165 | 1.00 | KMT2A (0.69) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL8729224 | 0.95 | KMT2A (0.67) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL9803295 | 0.91 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL4509654 | 0.90 | KMT2A (0.77) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL30167982 | 0.88 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL10787479 | 0.88 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL9402647 | 0.86 | KMT2A (0.73) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL9337589 | 0.85 | KMT2A (0.71) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL2003637 | 0.85 | KMT2A (0.71) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL6932542 | 0.84 | KMT2A (0.75) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |