Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.66 |
| ▸ | PLG | P00747 | 1/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.66 |
| ▸ | C1S | P09871 | 1/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932542 | 0.95 | KMT2A (0.75) | KMT2ANR4A2PRSS1F2PLG | |
| SCHEMBL9803295 | 0.94 | KMT2A (0.80) | KMT2ANR4A2PRSS1PLA2G4BAKR1C3 | |
| SCHEMBL4509654 | 0.93 | KMT2A (0.77) | KMT2ANR4A2PRSS1PLA2G4BAKR1C3 | |
| SCHEMBL10787479 | 0.91 | KMT2A (0.80) | KMT2ANR4A2PRSS1PLA2G4BPKM | |
| SCHEMBL30167982 | 0.91 | KMT2A (0.80) | KMT2ANR4A2PRSS1PLA2G4BPKM | |
| SCHEMBL27417012 | 0.90 | KMT2A (0.65) | KMT2ANR4A2PRSS1F2PLG | |
| SCHEMBL14384310 | 0.89 | KMT2A (0.63) | KMT2ANR4A2PLA2G4BPKMHTT | |
| SCHEMBL2934559 | 0.88 | KMT2A (0.71) | KMT2ANR4A2PRSS1PLA2G4BAKR1C3 | |
| SCHEMBL9337589 | 0.88 | KMT2A (0.71) | KMT2ANR4A2PRSS1PLA2G4BAKR1C3 | |
| SCHEMBL9853997 | 0.87 | NR4A2 (0.69) | KMT2ANR4A2PLA2G4BAKR1C3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |