Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853823 | 0.93 | ATM (0.53) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL373897 | 0.93 | ATM (0.53) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9001634 | 0.92 | ATM (0.40) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL10537156 | 0.91 | ATM (0.39) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3482740 | 0.87 | HCAR2 (0.59) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9242304 | 0.87 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9245022 | 0.87 | ATM (0.52) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3482742 | 0.87 | HCAR2 (0.59) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9244986 | 0.87 | ATM (0.52) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9242316 | 0.87 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600269-B1 | Soft ocular lens material | MENICON CO LTD (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0219884-B1 | HARD CONTACT LENS MATERIAL | Tomei Sangyo Kabushiki Kaisha (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |