SCHEMBL373897

SCHEMBL373897

C[Si](C)(C)O[Si](CCCOC(=O)/C=C/C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
HCAR2 Q8TDS4 6/20 0.47
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 2/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
APP P05067 5/20 0.33
PRKCA P17252 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853823 1.00 ATM (0.53) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3482740 0.93 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9242316 0.93 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9242304 0.93 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3482742 0.93 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8733190 0.93 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244986 0.93 ATM (0.52) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9245022 0.93 ATM (0.52) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10025714 0.92 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL35808 0.91 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015099-A1 NON BIO-ADHESIVE POLYMER COATING COMPOSITION, ARTICLES AND DEVICES THEREOF GENERAL ELECTRIC COMPANY (US) 2011-01-20 US claimed
JP-62039589-A None JP disclosed
JP-10251352-A None JP disclosed
JP-9077831-A None JP disclosed
US-12428390-B2 Chromene compound and photochromic optical article TOKUYAMA CORPORATION (JP) 2025-09-30 US disclosed
EP-3822296-B1 POLYMER MATERIAL MENICON CO LTD (JP) 2025-09-10 EP disclosed
WO-2025094241-A1 COMPOSITE MEMBRANE 株式会社メニコン 2025-05-08 WO disclosed
US-20250115701-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2025-04-10 US disclosed
US-12239527-B2 Method of absorbing or discharging water of ophthalmic medical device and ophthalmic medical device TOHOKU UNIVERSITY (JP) 2025-03-04 US disclosed
US-12209154-B2 Polymer material MENICON CO., LTD. (JP) 2025-01-28 US disclosed
EP-0524557-A2 Ocular lens material Menicon Co., Ltd. (JP) 1993-01-27 EP disclosed
US-5142009-A Crosslinked blend of fumaric acid diesters TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed
US-4868260-A OXYGEN PERMEABILITY TOMEI SANGYO KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
EP-0219884-A2 Hard contact lens material Tomei Sangyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed
EP-0215435-A1 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-03-25 EP disclosed
JP-S6239589-A BIS(SILOXANYLALKYL)FUMARATE AND PRODUCTION THEREOF SEIKO EPSON CORP 1987-02-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428390-B2 Chromene compound and photochromic optical article CRY1, CRY2, RAD51 ATM 908/4885HCAR2 3379/4885MAPT 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.