Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399626 | 0.85 | TAAR1 (0.74) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL8731016 | 0.84 | TAAR1 (0.60) | TAAR1IDO1AGXTMAOBPYCR1 | |
| SCHEMBL5240585 | 0.81 | TAAR1 (0.68) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL9660784 | 0.79 | TAAR1 (0.65) | TAAR1IDO1AGXTMAOBTDP1 | |
| SCHEMBL19524669 | 0.79 | TAAR1 (0.65) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL705920 | 0.79 | TAAR1 (0.65) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL30688447 | 0.79 | TAAR1 (0.65) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL235748 | 0.77 | TAAR1 (1.00) | TAAR1IDO1AGXTMAOBSMN1; SMN2 | |
| SCHEMBL1513555 | 0.77 | TAAR1 (0.63) | TAAR1IDO1AGXTMAOBPYCR1 | |
| SCHEMBL1646500 | 0.77 | TAAR1 (0.63) | TAAR1IDO1AGXTMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| CN-1034864-C | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1997-05-14 | — | — | CN | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| CN-1069728-A | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1993-03-10 | — | — | CN | disclosed |