SCHEMBL8733207

SCHEMBL8733207

CCc1cccc(CCl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
MGLL Q99685 1/20 0.42
BCL2 P10415 1/20 0.40
RAPGEF4 Q8WZA2 1/20 0.40
TRPA1 O75762 1/20 0.39
IDO1 P14902 1/20 0.39
KIF11 P52732 2/20 0.38
NISCH Q9Y2I1 1/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL166894 0.87 TP53 (0.61) TP53CYP1A2CYP2A6MGLLBCL2
SCHEMBL225197 0.87 TSHR (0.54) TSHRCYP1A2IDO1MAPTALDH1A1
Ammonia Solution, Strong SCHEMBL28805948 0.84 TP53 (0.58) TP53CYP1A2CYP2A6MGLLBCL2
SCHEMBL28256639 0.84 TP53 (0.58) TP53CYP1A2CYP2A6MGLLBCL2
Benzene SCHEMBL9785236 0.84 TP53 (0.67) TP53CYP1A2CYP2A6MGLLBCL2
SCHEMBL18415678 0.83 ALDH1A1 (0.44) TSHRCYP1A2CYP2A6ALDH1A1MAPK1
Ethyne SCHEMBL28293458 0.81 TP53 (0.55) TP53CYP1A2CYP2A6MGLLBCL2
Ethylene SCHEMBL27256792 0.81 TP53 (0.55) TP53CYP1A2CYP2A6MGLLBCL2
Hydrogen Peroxide SCHEMBL11520377 0.81 TP53 (0.63) TP53CYP1A2CYP2A6MGLLBCL2
Methyl Alcohol SCHEMBL28745884 0.81 TP53 (0.55) TP53CYP1A2CYP2A6MGLLBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103980088-A Method of preparing floralozone intermediate SUQIAN KESI CHEM CO LTD 2014-08-13 CN claimed
CN-103965031-A Preparation method of floralozone SUQIAN KESI CHEM CO LTD 2014-08-06 CN claimed
CN-115960048-B Cimetidine Process for the preparation of guanidine 常州安迪沃克医药科技有限公司 2025-01-24 CN disclosed
US-11667602-B2 Compounds and their use ASTRAZENECA AB (SE) 2023-06-06 US disclosed
CN-115960048-A Preparation method of cimetidine 常州安迪沃克医药科技有限公司 2023-04-14 CN disclosed
EP-3831861-A1 DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME SKC Co., Ltd. (KR) 2021-06-09 EP disclosed
EP-2729519-B1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS INC (US) 2019-05-15 EP disclosed
CN-109111463-A The manufacturing method of aromatic compound DIC株式会社 2019-01-01 CN disclosed
US-9580749-B2 Dyes and labeled molecules BIOTIUM, INC. (US) 2017-02-28 US disclosed
US-8877437-B1 Methods of using dyes in association with nucleic acid staining or detection BIOTIUM, INC. (US) 2014-11-04 US disclosed
CN-103980088-A Method of preparing floralozone intermediate SUQIAN KESI CHEM CO LTD 2014-08-13 CN disclosed
CN-1017055-B Process for producing aromatic amine resin MITSUI TOATSU CHEMICALS (JP) 1992-06-17 CN disclosed
US-5028581-A Odorless multi-valent metal modified products of salicyclic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-07-02 US disclosed
US-5023366-A Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-06-11 US disclosed
EP-0361040-A2 Odorless multi-valent metal modified products of salicylic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-04-04 EP disclosed
CN-1032806-A Aromatic amine resin, its preparation method and application in thermosetting resin composition MITSUI TOATSU CHEMICALS (JP) 1989-05-10 CN disclosed
EP-0268878-A2 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-01 EP disclosed
US-3993852-A DIALKYL PHENYLALKANEPHOSPHONATES CIBA-GEIGY AG (CH) 1976-11-23 US disclosed
US-3961050-A Insecticidal compositions and methods of killing insects using benzylthiomethylenephosphonamidates and phosphoramidates VELSICOL CHEMICAL CORPORATION (US) 1976-06-01 US disclosed
US-3954973-A ALKYL HALIDES AMERICAN CYANAMID COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667602-B2 Compounds and their use RXFP1, RXFP3, RXFP2 TP53 4491/4885TSHR 436/4885CYP1A2 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.