SCHEMBL8733216

SCHEMBL8733216

CC(O)NC(O)=S.NC(O)=S

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286393 0.80 NPSR1 (0.33) DPP4
SCHEMBL16628390 0.78 NPSR1 (0.32) DPP4
Ammonia Solution, Strong SCHEMBL28489275 0.78 NPSR1 (0.32) DPP4
SCHEMBL16628376 0.78 NPSR1 (0.32) DPP4
Selenium SCHEMBL11492109 0.78 NPSR1 (0.32) DPP4
SCHEMBL1551404 0.77
SCHEMBL28932016 0.75 TSHR (0.39)
SCHEMBL17514080 0.72 CA12 (0.52)
Isopropyl Alcohol SCHEMBL9858002 0.72 ALDH1A1 (0.46)
Isobutane SCHEMBL9349479 0.71 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773231-A Treatment for atherosclerosis and other cardiovascular and inflammatory diseases EMORY UNIVERSITY (US) 1998-06-30 US disclosed
US-4508909-A Synthesis of hydroxyethyltetrazolethiol and etherified intermediates therefor SHIONOGI & CO., LTD. (JP) 1985-04-02 US disclosed