SCHEMBL8733231

SCHEMBL8733231

C[CH]CCc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
CYP2A6 P11509 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
GPR52 Q9Y2T5 1/20 0.44
IDO1 P14902 1/20 0.44
HRH3 Q9Y5N1 3/20 0.42
KCNH2 Q12809 1/20 0.42
IGF1R P08069 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ACHE P22303 1/20 0.40
AGXT P21549 2/20 0.39
CHKA P35790 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
HRH1 P35367 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11639779 0.86 CYP1A2 (0.48) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL105975 0.81 CYP1A2 (0.48) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL713023 0.81 CYP1A2 (0.48) CYP1A2CYP2A6TAAR1GPR52IDO1
P-Xylene SCHEMBL11767119 0.81 CYP1A2 (0.48) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL6083273 0.78 CYP1A2 (0.50) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL8476153 0.78 CYP1A2 (0.50) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL11539924 0.78 TAAR1 (0.50) TAAR1IDO1L3MBTL1
SCHEMBL432651 0.78 TAAR1 (0.50) CYP1A2TAAR1IDO1KCNH2IGF1R
SCHEMBL1611960 0.78 CYP1A2 (0.50) CYP1A2CYP2A6TAAR1GPR52IDO1
SCHEMBL364888 0.78 CYP2A6 (0.50) CYP1A2CYP2A6TAAR1GPR52IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3607002-A1 COLORANT MIXTURES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2020-02-12 EP disclosed
WO-2018184770-A1 COLORANT MIXTURES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2018-10-11 WO disclosed
CN-1119337-C Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-08-27 CN disclosed
CN-1239957-A Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide BAYER AG (DE) 1999-12-29 CN disclosed
CN-1239955-A Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 1999-12-29 CN disclosed
WO-1998043649-A2 AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-10-08 WO disclosed