Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6083107 | 0.86 | IGF1R (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL19031453 | 0.82 | GPR52 (0.49) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL8733231 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL3079938 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL1611960 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL364888 | 0.76 | CYP2A6 (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL2132364 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL11661465 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL8476153 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL11288839 | 0.76 | CYP1A2 (0.68) | CYP1A2CYP2A6TAAR1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| CN-1377263-A | Neuropathy improves containing nitrogenous compounds as the active ingredient | TEIJIN LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |