SCHEMBL8733246

SCHEMBL8733246

O=C=NC1CCC(C[C@H]2CC[C@H](N=C=O)CC2)CC1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
APLNR P35414 1/20 0.36
CYP3A4 P08684 1/20 0.35
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6318341 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL22543 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL5902920 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL7192102 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL10507329 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL23743495 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
SCHEMBL5903114 1.00 ALDH1A1 (0.54) ALDH1A1APLNRCYP3A4KMT2A
Methane SCHEMBL10803844 0.98 ALDH1A1 (0.52) ALDH1A1APLNRCYP3A4
SCHEMBL4556661 0.93 ALDH1A1 (0.48) ALDH1A1APLNRCYP3A4
SCHEMBL1179083 0.93 ALDH1A1 (0.48) ALDH1A1APLNRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0606832-B1 Radiopaque polyurethanes BAYER AG (US) 1998-04-08 EP claimed
US-4879408-A Cycloaliphatic diisocyanates optionally in the form of isomer mixtures and a process for their production BAYER AKTIENGESELLSCHAFT (DE) 1989-11-07 US disclosed
EP-0104531-B1 CYCLOALIPHATIC DIISOCYANATES, POSSIBLY IN THE FORM OF A MIXTURE OF ISOMERS, METHOD FOR THEIR PREPARATION AND THEIR USE AS STARTING PRODUCTS IN THE PREPARATION OF SYNTHETIC PRODUCTS OF THE POLYURETHANE TYPE BAYER AG (DE) 1985-11-21 EP disclosed
EP-0104551-B1 CYCLOALIPHATIC DIISOCYANATES, POSSIBLY IN THE FORM OF A MIXTURE OF ISOMERS, METHOD FOR THEIR PREPARATION AND THEIR USE AS STARTING PRODUCTS IN THE PREPARATION OF SYNTHETIC PRODUCTS OF THE POLYURETHANE TYPE BAYER AG (DE) 1985-11-13 EP disclosed
EP-0104531-A1 Cycloaliphatic diisocyanates, possibly in the form of a mixture of isomers, method for their preparation and their use as starting products in the preparation of synthetic products of the polyurethane type BAYER AG (DE) 1984-04-04 EP disclosed
EP-0104551-A1 Cycloaliphatic diisocyanates, possibly in the form of a mixture of isomers, method for their preparation and their use as starting products in the preparation of synthetic products of the polyurethane type BAYER AG (DE) 1984-04-04 EP disclosed