Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175084 | 0.98 | TSHR (0.57) | TSHRSIGMAR1LMNAPYCR1ALDH1A1 | |
| SCHEMBL9172279 | 0.93 | TSHR (0.59) | TSHRSIGMAR1LMNAPYCR1ALDH1A1 | |
| SCHEMBL24767335 | 0.84 | TSHR (0.56) | TSHRSIGMAR1LMNAALDH1A1HPGD | |
| SCHEMBL8733292 | 0.84 | TSHR (0.56) | TSHRSIGMAR1LMNAALDH1A1HPGD | |
| SCHEMBL8208661 | 0.84 | TSHR (0.56) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL7471982 | 0.84 | TSHR (0.56) | TSHRSIGMAR1LMNAPYCR1ALDH1A1 | |
| SCHEMBL6998770 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL3029808 | 0.82 | TSHR (0.57) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL9175089 | 0.82 | TSHR (0.57) | TSHRSIGMAR1LMNAPYCR1ALDH1A1 | |
| SCHEMBL28087019 | 0.82 | TSHR (0.57) | TSHRSIGMAR1LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| CN-1034864-C | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1997-05-14 | — | — | CN | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| CN-1069728-A | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1993-03-10 | — | — | CN | disclosed |