Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545015 | 0.89 | TSHR (0.62) | TSHRSIGMAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL1048614 | 0.89 | TSHR (0.62) | TSHRSIGMAR1LMNAALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL1169677 | 0.88 | TSHR (0.61) | TSHRSIGMAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL5096939 | 0.86 | ALDH1A1 (0.52) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL9175084 | 0.85 | TSHR (0.57) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL8867687 | 0.84 | TSHR (0.61) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL8733290 | 0.83 | TSHR (0.56) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL9172279 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL81981 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL1935375 | 0.83 | TSHR (0.69) | TSHRSIGMAR1LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023283-B | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023283-B | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-1056749-B1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2003-02-19 | — | — | EP | disclosed |
| US-6369064-B1 | MYOCARDIAL INFARCTION AND UNSTABLE ANGINA; P2T-RECEPTOR ANTAGONISTS; ANTITHROMBOTIC AGENTS; 7-(SUBSTITUTED AMINO) -5-(THIO)-3H-1,2,3-TRIAZOLO(4,5-D)PYRIMIDIN-3-YL) -CYCLOPENTANECARBOXAMIDES | ASTRAZENECA AB (SE) | 2002-04-09 | — | — | US | disclosed |
| CN-1291193-A | Novel triazolo (4.5-d) pyrimidine compounds | ASTRA ZENIC BRITISH CO LTD (GB) | 2001-04-11 | — | — | CN | disclosed |
| EP-1056749-A1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999041254-A1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |