SCHEMBL8733336

SCHEMBL8733336

C=CC(CC(C)=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.47
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.42
LMNA P02545 2/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
KMT2A Q03164 2/20 0.39
ALB P02768 1/20 0.39
CYP2C9 P11712 1/20 0.39
PCSK7 Q16549 1/20 0.39
HSD17B10 Q99714 1/20 0.39
VKORC1 Q9BQB6 1/20 0.39
MEN1 O00255 1/20 0.39
BRD4 O60885 1/20 0.38
GABBR2 O75899 1/20 0.38
GABBR1 Q9UBS5 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539961 0.86 CYP2C19 (0.40) FFAR1CYP2C19ALDH1A1KDM4EMAPT
SCHEMBL3270768 0.85 FFAR1 (0.52) FFAR1CYP2C19MAPTLMNAGABBR2
SCHEMBL14071758 0.85 FFAR1 (0.52) FFAR1CYP2C19MAPTLMNAGABBR2
SCHEMBL13084164 0.84 FFAR1 (0.49) FFAR1CYP2C19ALDH1A1KDM4EMAPT
SCHEMBL9674054 0.84 STAT3 (0.46) FFAR1CYP2C19ALDH1A1KDM4EMAPT
SCHEMBL27556646 0.83 ALDH1A1 (0.44) CYP2C19ALDH1A1KDM4EMAPTHPGD
SCHEMBL8217036 0.83 HPGD (0.41) FFAR1CYP2C19ALDH1A1HPGDLMNA
SCHEMBL27163620 0.81 FFAR1 (0.47) FFAR1CYP2C19ALDH1A1MAPTHPGD
SCHEMBL9116270 0.80 ALDH1A1 (0.42) CYP2C19ALDH1A1KDM4EMAPTHPGD
SCHEMBL9116274 0.80 ALDH1A1 (0.42) CYP2C19ALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833883-A1 CYCLOHEXYL-SUBSTITUTED ALKANOLS Henkel Kommanditgesellschaft auf Aktien (DE) 1998-04-08 EP disclosed
WO-1996041853-A1 CYCLOHEXYL-SUBSTITUTED ALKANOLS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-12-27 WO disclosed
WO-1996039371-A1 AROMATIC CARBONYL COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-12-12 WO disclosed
WO-1995030406-A1 USE OF 3-PHENYL-4-PENTENALS AND THEIR DERIVATIVES AS SCENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-11-16 WO disclosed