Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733492 | 0.89 | THRA (0.48) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8733497 | 0.88 | PPARD (0.45) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8729949 | 0.87 | THRA (0.44) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8727835 | 0.86 | THRA (0.44) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8727839 | 0.86 | THRA (0.44) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8727832 | 0.86 | THRA (0.44) | PPARDTHRATHRBRARBPTPN11 | |
| SCHEMBL8457375 | 0.84 | PTPN11 (0.49) | THRATHRBRARBPTPN11SMPD1 | |
| SCHEMBL9640278 | 0.83 | PTPN11 (0.54) | THRATHRBRARBPTPN11 | |
| SCHEMBL9641454 | 0.83 | PTPN11 (0.54) | THRATHRBRARBPTPN11 | |
| SCHEMBL9641122 | 0.83 | PTPN11 (0.54) | THRATHRBRARBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703955-B1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECR DEFENCE BRIT (GB) | 1998-11-11 | — | — | EP | disclosed |
| EP-0703955-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |