Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 6/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654313 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8064225 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8735871 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8733976 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL12917092 | 0.81 | KCNH2 (0.46) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9748530 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8064229 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL9097687 | 0.78 | TOP2A (0.46) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8137973 | 0.78 | TOP2A (0.46) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8138702 | 0.78 | TOP2A (0.46) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |