SCHEMBL8733685

SCHEMBL8733685

C[Zr](C(=O)c1ccccc1)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7078763 0.75 GPR3 (0.33)
SCHEMBL868285 0.74 GPR3 (0.34) POLB
Hydrochloric Acid SCHEMBL8926582 0.73 GPR3 (0.32)
SCHEMBL6061528 0.72 POLB (0.33) POLB
SCHEMBL7795682 0.72 POLB (0.33) POLB
SCHEMBL8617779 0.70
Hydrochloric Acid SCHEMBL1135150 0.69
SCHEMBL7641853 0.69 GPR3 (0.31)
SCHEMBL7160430 0.68 MEN1 (0.33) KMT2AMEN1
SCHEMBL4453488 0.68 GPR3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed