Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313685 | 0.83 | ACHE (0.55) | BCHEACHEHTR2AHRH1KDM4E | |
| SCHEMBL877438 | 0.81 | HTR2A (0.56) | BCHEACHEHTR2A | |
| SCHEMBL30696221 | 0.81 | KDM4E (0.44) | BCHEACHEHTR2AHRH1KDM4E | |
| SCHEMBL11724087 | 0.80 | KDM4E (0.69) | BCHEACHEHTR2AHRH1KDM4E | |
| SCHEMBL6061696 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6060938 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL1449246 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6061312 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL407781 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6060761 | 0.80 | HTR2A (0.54) | BCHEACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839833-A2 | Catalyst systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 1998-05-06 | — | — | EP | disclosed |