SCHEMBL8733914

SCHEMBL8733914

CC1=Cc2ccccc2C1[Zr]C1C(C)=Cc2ccccc21.CCO[SiH2]C

nearest known ligand 0.30

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
BRCA1 P38398 1/20 0.30
HBB P68871 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630043 0.89 MAOB (0.33) LMNA
SCHEMBL7633026 0.88
SCHEMBL28230694 0.82 LMNA (0.33) LMNA
SCHEMBL29959660 0.82 LMNA (0.33) LMNA
SCHEMBL688487 0.82 LMNA (0.33) LMNA
SCHEMBL8732808 0.79
Chloromethane SCHEMBL3686216 0.79 LMNA (0.32) LMNA
SCHEMBL8732742 0.78 PDCD1 (0.30)
SCHEMBL28294142 0.77 LMNA (0.31) LMNA
SCHEMBL8779527 0.76 CYP11B1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0858462-A1 SUPPORTABLE BISCYCLOPENTADIENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1998-08-19 EP disclosed
WO-1997015582-A1 SUPPORTABLE BISCYCLOPENTADIENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed