Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733952 | 1.00 | NPSR1 (0.39) | NPSR1KDM4EPOLBLMNAMAPK1 | |
| SCHEMBL7049477 | 0.90 | NPSR1 (0.36) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL9562430 | 0.90 | NPSR1 (0.36) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL10400402 | 0.90 | NPSR1 (0.36) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL9676468 | 0.87 | MAPT (0.36) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL8775494 | 0.87 | MAPT (0.36) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL10351478 | 0.85 | MAPT (0.34) | NPSR1KDM4EPOLBLMNAMAPK1 | |
| SCHEMBL8437121 | 0.85 | POLB (0.39) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL9562451 | 0.85 | POLB (0.39) | NPSR1KDM4EPOLBLMNAGAA | |
| SCHEMBL10351480 | 0.85 | MAPT (0.34) | NPSR1KDM4EPOLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |