Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187513 | 0.93 | TSHR (0.45) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL30469492 | 0.93 | TSHR (0.45) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL1050419 | 0.91 | TSHR (0.44) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL30469491 | 0.91 | TSHR (0.44) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL29140660 | 0.79 | TSHR (0.50) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL8737418 | 0.77 | TSHR (0.33) | GLAPOLBGAATSHR | |
| SCHEMBL1554371 | 0.77 | TSHR (0.39) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL1554380 | 0.77 | TSHR (0.39) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL1554300 | 0.77 | TSHR (0.39) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL8847029 | 0.75 | TSHR (0.43) | GAATSHRTDP1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675915-B1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORP (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0675915-A1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORPORATION (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5449742-A | Optical waveguides with cores | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| WO-1994014874-A1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |