Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 8/20 | 0.73 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.73 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734134 | 0.86 | KCNK3 (0.76) | KCNK3KCNK9KCNH2MAPTMEN1 | |
| SCHEMBL19156982 | 0.84 | KCNK3 (0.91) | KCNK3KCNK9KCNH2MAPTCYP1A2 | |
| SCHEMBL12764067 | 0.84 | KCNK3 (0.91) | KCNK3KCNK9KCNH2MAPTMEN1 | |
| SCHEMBL1816127 | 0.81 | MEN1 (0.84) | KCNK3KCNK9GPR17MAPTMEN1 | |
| SCHEMBL4241893 | 0.81 | KMT2A (0.79) | KCNK3KCNK9MAPTMEN1KMT2A | |
| SCHEMBL4610855 | 0.80 | MEN1 (0.72) | KCNK3KCNK9GPR17KCNH2MAPT | |
| SCHEMBL30739887 | 0.79 | MEN1 (0.78) | KCNK3KCNK9KCNH2MAPTCYP1A2 | |
| SCHEMBL10269450 | 0.79 | MEN1 (0.78) | KCNK3KCNK9KCNH2MAPTCYP1A2 | |
| SCHEMBL8361568 | 0.79 | KCNK3 (0.73) | KCNK3KCNK9MAPTMEN1KMT2A | |
| SCHEMBL31556825 | 0.79 | KCNK3 (0.73) | KCNK3KCNK9MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |