Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.76 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822889 | 0.87 | MEN1 (0.78) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL1811680 | 0.87 | L3MBTL1 (0.82) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL2077842 | 0.87 | KCNK3 (0.81) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL6802691 | 0.87 | KMT2A (0.78) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL8734140 | 0.86 | KCNK3 (0.73) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2106088 | 0.86 | L3MBTL1 (0.80) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL12764067 | 0.86 | KCNK3 (0.91) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL19156982 | 0.86 | KCNK3 (0.91) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2105161 | 0.86 | KCNK3 (0.79) | KCNK3KCNK9L3MBTL1KMT2AMEN1 | |
| SCHEMBL8361568 | 0.81 | KCNK3 (0.73) | KCNK3KCNK9L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |